Double Strength! from Source Naturals. This SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients. Dozens of clinical studies have demonstrated that SAM-e supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. Studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe is present in every living cell in the body. However, levels of SAM-e tend to decline with age.
SAM-e and Homocysteine
One of the byproducts of normal SAMe metabolism is homocysteine. When there are adequate supplies of the metabolites, such as B6, B12 and folic acid, required for the synthesis and regeneration of SAMe, homocysteine breakdown occurs either through re-methylation or through trans-sulfuration. These processes turn homocysteine into glutathione, a powerful antioxidant. Therefore, supplementation with B6, B12 and Folic Acid or taking Homocysteine Protection Factors (PF) may insure proper function of SAMe.
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SAM-e (S-Adenosylmethionine) is an amino acid derivative that has been clinically proven to benefit brain and joint function. Found in all living cells, SAM-e is also called "activated" methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have indentified the following benefits of SAM-e 200:
Joint Strenght SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.
Brain Metabolism SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-Dopa, Dopamine and Related Hormones, Epinephrine and Phosphatidylcholine (a component of Lecithin).
Liver SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.
Longevity Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.
One tablet one to three times daily, or as recommended by your health care professional. Take tablets on an empty stomach. Suitable for vegetarians and Hypoallergenic: contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no preservatives or artificial color, flavor or fragrance.
Warnings:
Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors and MAO Inhibitors should consult a physician before using. Individuals with bi-polar disorder or manic depression should not use SAM-e.
PLACE OUT OF REACH OF CHILDREN.
Packaged Weight:
2.7
Manufacturer Info:
Source Naturals
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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